Allergan's Mohawk evergreening patent deal draws criticism, but ultimately may flop

Is Patent “Evergreening” Restricting Access to Medicine/Device Combination Products?

BACKGROUND Not all new drug products are truly new. Some are the result of marginal innovation and incremental patenting of existing products, but in such a way that confers no major therapeutic improvement. This phenomenon, pejoratively known as "evergreening", can allow manufacturers to preserve market exclusivity, but without significantly bettering the standard of care. Other studies specul...

The Right Hand Draws the Trees, But the Left Draws the Forest?

Spatial processing is lateralized: the right hemisphere is optimized for perceiving global aspects of space ("seeing the forest"), while the left hemisphere specializes in perceiving local aspects of space ("seeing the trees"). However, less is known about how the information is shared across the hemispheres and which areas within the corpus callosum are required for transferring and integratin...

Implementing New Regulation Promotes Health but May Increase Inequality

Feminist Art Criticism: Issues in Feminist Criticism Written About the Work of May Stevens

Patent foramen ovale may be causal for the first stroke but unrelated to subsequent ischemic events.

BACKGROUND AND PURPOSE Studies with very long follow-up are scarce in patients with cryptogenic stroke and patent foramen ovale (PFO). Little is known about the etiology of recurrent cerebrovascular events (CVE) in PFO patients. METHODS We collected information on recurrent CVE in 308 patients with cryptogenic stroke and PFO and sought to determine concurrent stroke causes that had emerged or...